Cagrilintide is a long-acting amylin analogue that is primarily used in weight management. It helps with weight loss by mimicking the effects of amylin, reducing energy intake and regulating food choices and preferences. Cagrilintide has a half-life of about 7-8 days, which means it stays active in the body for a longer period of time, helping to maintain a stable effect .
CAS No. | 53-84-9 | Molecular Weight | 663.425 |
Molecular Formula | C21H27N7O14P2 | Melting Point | 140 - 142ºC |
Cagrilintide has shown good safety and tolerability in clinical studies. In a Phase 1b clinical trial, Cagrilintide was used in combination with Semaglutide (GLP-1 analogue), which showed a significantly higher percentage of weight loss in participants than in the placebo group. Specifically, the Cagrilintide 1.2 mg and 2.4 mg groups had average weight loss percentages of -15.7% and -17.1%, respectively, compared with -9.8% in the placebo group.
The market for Cagrilintide is promising, especially in the field of obesity treatment. Novo Nordisk is studying CagriSema, its mixture with semaglutide, which is expected to help patients lose at least 25 percent of their body weight and may cause no more side effects than semaglutide alone. CagriSema is also exploring its potential as a treatment for type 2 diabetes.
Cagrilintide’s development background shows its potential in weight management. Novo Nordisk is actively advancing its clinical studies to demonstrate CagriSema’s superiority and maintain its leading position in the treatment of obesity.